Article abstract

International Journal of Biotechnology and Food Science

Review Article | Published July 2018 | Volume 6, Issue 2, pp. 18-32

 

Anti-ulcer Activity of Some Selected Medicinal Plants: A review

 

 

 

 

 

Osman Albarri1*

Khaled W. K. Alzeini2

Işıl Var3

Amani Boushihassal1

Melda Meral4

Cansu Önlen4

Başak Bedir4

Suna Kızılyıldırim4

Fırat Karslı4

Fatih Köksal4

 

  Email Author

Tel: +905367734765.

 

1.    Institute of Natural and Applied Sciences (Fen Bilimleri Enstitüsü), Department of Biotechnology, Cukurova University, 01330 Balcali, Adana, Turkey.

 

2.    Faculty of Biosciences and Medical Engineering, Department of Biotechnology and Medical Engineering, Universiti Teknologi Malaysia (UTM),81310 Johor Bahru, Johor, Malaysia.

    

3.    Department of Food Engineering, Agricultural Faculty, Cukurova University, TR-01100 Adana, Turkey.

 

4.    Department of Medical Microbiology, Faculty of Medicine, Çukurova University, TR-01100 Adana, Turkey.

 

 

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Citation: Albarri O, Alzeini KWK, Var I, Boushihassal A, Meral M, Önlen C, Bedir B, Kızılyıldırim S, Karslı F, Köksal F (2018). Anti-ulcer Activity of Some Selected Medicinal Plants: A review. Int. J. Biotechnol. Food Sci. 6(2): 18-32.

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 Abstract 


A peptic ulcer is an ulcer of one of those areas of the gastrointestinal tract that are usually acidic. Peptic ulcer formation occurred due to the acid of excess, peptic activity in gastric juice as well as a breakdown in mucosal defenses. Some of anti-ulcer medicines such as proton pump inhibitors and H2 receptor antagonists are used for peptic ulcer treatment. However, these drugs have shown disease relapse, side effects, and even drug interactions. Many medicinal plants exhibit anti-ulcer activity and found useful in the treatment of peptic ulcer. The purpose of this review is to know more about the anti-ulcer properties of the medicinal plants. Serjania marginata (HESM) leaves, thymol obtained from Thymus, Origanum and Cuphea aequipetala infusion (CAI) In this review there is information about some kinds of plants which are very useful in treating peptic ulcer disease such as hydroalcoholic extract obtained from S. marginata (HESM) leaves, thymol obtained from Thymus, Origanum and CAI. These plants were studied by their mechanisms underlying to the gastroprotective effect of thymol and HESM. Furthermore, the study reported the potential effect of involvement of some factors of the protective effect of medical extract, such as prostaglandins (PG), nitric oxide (NO), and a hydrogen sulfide (H2S). Side the effect of these factors in gastro protective, and finally the paper clarified some local mechanisms of actions of some compounds that were involved in mucosal defense or injury.

Keywords  HESM   thymol   CAI   anti-ulcer   medicinal plant 



 

Copyright © 2018 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0




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