New advances in molecular mechanism of microbial hexavalent chromium reduction

 

Luming Zou, Pu Liu and Xiangkai Li*

 

Review Article | Published September 2013

International Journal of Biotechnology and Food Science, Vol. 1(3), pp. 46-55

 

 

^{Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Tianshui Nan Lu #222, Lanzhou, Gansu, 730000, P. R. China.}

 

*Corresponding author. E-mail: xkli@lzu.edu.cn.  Tel: 86-931- 8912561. Fax: 86-931-8912560.

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Chromate contamination causes serious environmental problem, microbial reduction of chromate from its most toxic form Cr (VI) to Cr (III) made it to be a potential way to remediate chromate contamination. We concluded the molecular mechanism of microbial reduction of chromate, ChrR is a four-electron transfer chromate reductase, it reduces chromate to trivalent chromium directly, nitroreductase reduces chromate mixed di- and semi-electron transportation, they are both flavoprotein, FMN are their active center, cytochrome c reduces chromate because of the redox potential of its hemes. And, we also found a new pathway in which glutaredoxin acts as the role electron donor.

 

Keywords: Microbial chromate reduction, ChrR, nitroreductase, cytochrome c, chromate remediation.

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Citation: Luming Zou, Pu Liu, Xiangkai Li (2013). New advances in molecular mechanism of microbial hexavalent chromium reduction. Int. J. Biotechnol. Food Sci. 1(3): 46-55

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